Consistently above the national birth rate average in all measured categories*

Ovarian Rejuvenation: PRP-Platelet-Rich Plasma



We can take women’s own blood and centrifuge and separate out layers and extract a portion of it called “Platelet-Rich Plasma”, nicknamed PRP. That concentrated portion of your blood, PRP, contains various chemical factors that can cause the blood vessels to dilate and cause increased blood flow. This increased blood supply could stimulate ovarian stem cells so that better or more viable eggs to be available. For women who are not yet or ever comfortable using donor eggs, this ovarian stimulation may offer a chance to get the eggs needed for their baby. This process is called “PRP treatment for IVF”.

The PRP therapy process involves collecting your blood, processing it, and extracting the protein-rich plasma, then performing a PRP injection directly into the ovarian tissue. This ovarian PRP therapy could be uncomfortable and so we perform it under light sedation and some local anesthesia. Although there are many protocols and no consensus (as this treatment is new and not yet mainstream), it makes the most sense to do this 3 months before the intended cycle. Some programs recommend multiple treatments as their protocol. At Fertility Partnership, we perform the treatment and monitor your blood and ultrasound antral follicle counts-AFC every 2 weeks, if possible, and will repeat the protocol based on those results. Once we see changes in hormones and/or follicles we will plan your cycle.

It has also been shown in clinical studies that PRP injections with a catheter into the uterus can thicken the thin endometrium. It is believed that those factors that stimulate eggs in the ovary, and in the uterus, stimulate the cells that make the endometrium. For women who have struggled to get their lining thick enough for a transfer, this may be an answer for them.

PRP treatment for in vitro fertilization (IVF), or ovarian rejuvenation, is very low risk to the patient. PRP has been injected into humans for many reasons. it has been used for everything from nerve regeneration to Plantar Fasciitis. The blood products are the patient’s own and infection is rare. We cover you with oral antibiotics to add safety. Pain felt by the patient is variable. Some women can have PRP therapy done without any anesthesia, but we believe that some lidocaine to the vaginal wall and some sedation make it very tolerable.

In Summary, PRP injection is safe. For a woman who is potentially looking at having to give up on her own ovarian reserve, we believe that this PRP treatment offers hope for a good result to some patients although we are not yet sure which patients.  Preliminary studies and anecdotal reports support the safety and the likelihood that future studies will show a clear benefit for some people. We are monitoring our progress and hope to identify those most likely to see a benefit. However, in the meantime, there are women who need hope now, and so, Fertility Partnership has joined those already offering this PRP treatment in our usual fertility clinic style: keep it as inexpensive as possible without lowering success.

For information on ovarian rejuvenation therapy or other fertility treatment, call the fertility center at 636-441-7770.


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69 Responses
        1. Dr. Elan Simckes

          Mary, since I am the Dr. I usually do not answer questions regarding finances. Amy Fischer the office manager does that. But I will tell you that our costs are under 9000 but that does not include medications and some freezing. We typically end up significantly lower than other places while maintaining success rates that are higher than most

      1. Lindsay Ferro

        I started my IVF journey at 38 . The first time I took a large amount of medication and retrieved six eggs three took until day 5 nothing. Four months later I went to get my eggs retrieved to wake up to the doctor giving me an iui because I ovulated overnight . Nothing . Six months later I took lots of medication and the two embryos I tested before implanting one had an extra chromosome and one lacked one .
        Six months later and confused and had zero results . I changed doctors . Which I’m now 41 and I just did MINI ivf which is the fourth time , but really the first time I actually implanted . I got pregnant heard the heart beat was on my 8 week . I tested very high for potassium one day and was on high dosage of progesterone after my high blood test I had a miscarriage . My partner has low sperm count , but the doctor insist it’s my eggs aren’t valuable the only way I’ll get pregnant is with a donner egg. I feel like I have wasted 80 grand for the runaround and now my time is running out.
        I believe I can have s child I feel my medication has always been too much and I am desperate for help. I was thinking about doing iui because it’s less medication and it’s still a chance . Do u think prp would be good choice for me ? Or can you tell me what I should do? I also have a odd condition called cprs it’s a neurological pain problem in my feet. I had a flair in both my ankles and the next day I had the high potassium band misscarrued as few days later.

    1. April Nakea Graves

      Dr said I need prp my ivf Dr is in new York.. how much will you charge me for prp? Even though my Dr is in new York but price is so high there

        1. Toni Long

          Hi, my partner and I are very interested in learning more about this procedure to determine if it is a fit for us. We got pregnant naturally last year but devastatingly lost our little girl halfway through the pregnancy for unknown reasons. How do I schedule a consult?

          1. Dr. Elan Simckes

            Yes, asbsolutely come in to see me. We need to understand what happened to you and then move forward. 6364417770

  1. Elizabeth

    Yes, I dream to have a baby right now. Many doctors failed to communicate with me because I am deaf then Covid pandemic was unexpected! I pray for a miracle this YEAR! 🙏🏽🙏🏽🙏🏽 Email me instead of call so I can understand better. Thank you

    1. Dr. Elan Simckes

      I would be honored to help. We could video id you read lips. Otherwisde we can text.
      What are the issues?

  2. Nicole

    I had an ectopic pregnancy on 8/20/2021 which led to emergency surgery on 8/27/2021 and haven’t conceived again since. I lost my left tube and ovary also due to that. What should I do?

    1. Dr. Elan Simckes

      I am so sorry that you are having such a hard time. It is very likely that the other tube was also injured. I believe that you should be looking at Invocell as a possible option.

    1. Dr. Elan Simckes

      I I understand but you are interested. Please call us at (636)-441-7770. We will be happy to help. My front desk does not speak Spanish however once you’re here in the office we will do well.

  3. Carmen

    I been trying to get pregnant from my boyfriend after havin two miscarriage one after another… doctors have told me that my tubes are blocked now that I can’t have no kids due to my tubes being blocked I cry every nd I pray every night for a miracle to happen I just want is one more baby can you please help me make my dream come true!

  4. Lydia

    I am 50 years old and still fertile. I am interested in PRP as an aide for achieving pregnancy. I had my first daughter at 41 and have been told I have a very unusually young reproductive system for my age. But at 50 I would like to do the PRP as a boost in my chances. Would you consider this procedure for me?

    1. Dr. Elan Simckes

      Lydia, as long as you’re not in menopause then we would consider doing that the rp procedure. We would like free to have some follicles visible and ultrasounds and measurable AntiMullerian Hormone. Feel free to call the office and schedule consultation, perhaps a phone call, I know that we are filling up for the September PRP sessions so our number is (636)-441-7770

      1. Selam

        I am 45 yrs old and I never got pregnant due to poor egg quality. I still have my menses can I be a candidate for PRP

        1. Dr. Elan Simckes

          Have you had any recent testing? AMH? Ultrasound?
          so the quick answer is possibly yes. We will arrange for this testing ( before and after). schedule soon because the coordinator, Erica says we are booked far in advance.

      2. Vos

        Dr. Elan,

        I would like to set up a phone call with you to discuss PRP. I just got my AMH labs back from Naturopathic Dr who is recommending that I see you. I tried calling your office to set up a phone call with you but I didn’t get any help. What do I need to do to set up a phone call with you? I look forward to talking with you soon!

        Thank you!

    1. Dr. Elan Simckes

      Jocelyn, we would be delighted and honored to take care of you. I wish I could tell you that a new sign language I only know a few bad words lol. If you want to schedule an appointment and you can test my cell phone at (314)-550-7550

  5. Cheyanne Causey

    I am a 23 year old female that was diagnosed at age 18 with AML leukemia and went into remission for a little over a year then relapsed. This time at 21, I received a bone marrow transplant and that has been successful ever since. Unfortunately with the high dose chemotherapy, my ovaries have stopped producing. The good thing is I was able to retrieve some eggs before my transplant but I know that IVF doesn’t guarantee pregnancy. My dream is to be a mother and if there is any way possible to make this happen I want to do everything in my power to do so. My question is am I a PRP candidate?

    1. Dr. Elan Simckes

      I am very
      I’m actually going to invite you to catch me to my cell phone because I am interested in seeing if it is possible for you.
      One Dr. Simckes
      (314)-550-7550 Please text

    2. Aracely Hernández

      Tengo problema de quedar embarazada hace desde quince años por qué me detectaron un quiste en un ovario y viene aquí a Estados Unidos y me hice un ultrasonido vaginal y me detectaron una fibroma en mi hutero y eso ase que no pase el esperma eso me explico mi doctor

    1. Dr. Elan Simckes

      Your choices are a tubal reversal or an IVF or Invocell procedure. You should read about Invovell.
      We are hav ing excellent results in patients post tubal ligation. The cost is similar to a reversal.
      We would want to evaluate your egg supply and sperm.
      You c

  6. I Ballard

    I have endometriosis along with endometriomas on my ovaries. I’m 42 and I’m trying to get pregnant. I’ve been to a fertility specialist who said egg donation is the only way. Can you help me?

    1. Dr. Elan Simckes

      Hello, I am sorry you are dealing with this. Egg donation may in fact be the only way but I am not sure
      if that is true. Have you had an attempt to collect eggs? what is your AMH? How large are your endometriomas? ,
      The main issue is your age, but we have helped many 42 year old women. I would be honored to evaluate you. Remember, you are in no rush for donor eggs. Up until age 55 according to the ASRM.

  7. Tee

    I am 41 and have had three unexplained early miscarriages. They did all the tests and hormones are good and they just said I have a low reserve left. For now my doc recommended letrozole for a few cycles. I just tried one so far and nothing yet so I’ma try again. I can get pregnant naturally but can’t keep them. Mayb it’s my egg quality because I have other children and never had this problem. Would I be a good candidate?

  8. Sandeep

    Hi I’m 39 two failed IVF 4 failed IUI. Am I the good candidate ? I want my own baby. My doctor suggests donor egg. What should I suggest? Thanks.

  9. Aimee De Oliveira

    Can PRP be done post hysterectomy due to adenomyosis for the purpose of extracting eggs for a bio child with surrogate?

    1. Dr. Elan Simckes

      Yes, absolutely. I would meet you first to make sure by ultrasound that I have safe access to your ovaries, get some blood work.
      Remember that this creation of embryos must be done according to FDA standards in order to put the embryos in a surrogate.
      If you live out of town plan for a PRP with us and at our intake we can discuss your bigger plans.

      1. Aimee De Oliveira

        Wonderful! I do live out of town (About 8 hour drive). How many visits might I need including the initial consult to perform the PRP and prepare the embryos for surrogacy? I am at the beginning of this process and have many unanswered questions and would need to plan for the travel and time off work.

  10. MElsayed

    Dr. Simcks, do you offer EnPLAF therapy in combination with PRP? I am 41 years old, and my AMH fluctuates between 0.9-1.34. I have regular menses. I think my big problem is egg quality, and I read that PRP alone is not effective in improving age-related bad egg quality, and EnPLAF has a better outcome since it has higher concentrations of growth factors. I did IVF 3 times, and the average egg retrieval was 5-8; the first two times, only one embryo made it to the blastocyst, tested, and was abnormal. In the last cycle, three embryos made it to the blastocyst, but I didn’t test any of them. I was planning to do one more IVF cycle in the summer (I will be 42 by that time), but I was looking for something to improve my egg quality, like EnPLAF or PRP.

  11. Rene

    I am 40 with undetectable AMH level. But, still had AFC on ultrasound. Irregular menses and high FSH level. I’ve been told I am going through perimenopause or early menopause due to prior surgery for endometriosis and fibroids. One round of semi natural IVF produced one egg that fertilized and made it to blastocyst stage but tested aneuploid. I took no medicine except for a Lupron trigger shot. I was never administered Clomid or Letrozole. I live far away in another state and wouldn’t be able to be under your continuous care for infertility. But, could I just get the PRP?

    Thank you

    1. Dr. Elan Simckes

      Hello, I appreciate you reaching out to fertility partnership. Yes you can come in for the PRP. Please call backup who coordinates this. (314)-548-3052

  12. Autumn

    Hi Dr Elan,

    I am so interested in this PRP procedure. I have been doing IVF for 8 years and not successful. Wonder if this could be my last rescue. Thank you.

    1. Dr. Elan Simckes

      Hello, perhaps it would help. If you are not willing to use a donor egg, this might be your only choice to improve your odds with your own eggs. Unfortunately, there are no good studies to prove that it is true. So why are we doing it? Because there have been a lot of stories, true, they are anecdotal, and not true science, But they speak of women who did see improvement. We decided to try it out since there’s little risk to it. We set up our program and decided to charge just a small fraction of what other people are charging. Let’s see if it works. After a year and over 150 cases, we are seeing and help some people. Nowhere near as many as we would like. we are those starting to see more details about the group that it helps. And so, do you know what your AMH is? It is a blood test. Have you had an ultrasound that looked at your ovaries? How old are you? If you’re interested then call the office and we can set up a phone conversation.

  13. Maureen Miranda

    Hello, I am 48 and have to adult children. I would like to have another child. Am I a candidate for PRP ovarian rejuvenation?

    1. Dr. Elan Simckes

      We will be willing to perform the procedure if you still have regular menses and your blood tests are still indicating some ovarian activity. Please a a blood test called AMH, antimullerian hormone.

  14. Mo

    The Greek Doctors that innovated the PRP procedure said it could reverse menopause, albeit temporarily. Why did you say in answer to someone’s question that it can’t? Is your own procedural method different from the Greek’s? Thank you.

    1. Dr. Elan Simckes

      Ok that is a fair question. First of all We have tried to help people who are “diagnosed” with menopause without success.
      I am not interested in reviving a woman’s ovulation for just a few months. I am only interested in helping women get pregnant.
      A woman in recent menopause with visible follicles is a candidate here. We have obtained eggs and made embryos in women with FSH levels in menopause territory.
      Since we do not have hard core data yet, I wish to reserve our work in people who a biological plausibility that it will work.
      But the groups you spoke of, although the innovators, they also have a stronger profit motive. we do not. We charge less than half.
      In other words we are trying to just help people get pregnant who we believe can.

  15. cheryl

    I am 51 now, I have been on this fertility journey for 7 years and I believe this year is my last year to have a child. But the problem now is that I have stopped my period for a year. due to cervices stignious and it came back for 2 months and left.
    I am beyond frustrated until saw this PRP Ovarian Rejuvenation. I would like to know do you believe this will be a benefit to me.

    1. Dr. Elan Simckes

      I would want to know your recent FSH levels and an AMH if you have one. Also, if a pelvic ultrasound was done to see follicles.

  16. Sharon

    I had three children. My only son died at the age of one. Had three miscarriages and one tube pregnancy. My last miscarriage was in 2021 and I got a d&c done. Right after my d&c was done. I developed adenomyosis. Birth control pills wasn’t helping. Went on the depo shot. Still was bleeding for two weeks. I decided to get Uterine artery embolization (uae) done. Stay on the depo for a year. Never bleed. Two years later I fond out my ovaries are declining. Fond out test results said I have Primary ovarian insufficiency and going through menopause at the age of 44 years old The doctor didn’t know when I went through menopause due to the fact I was on depo shot for a year and it can take up more two years. I don’t have hot flashes. I only am dry down below. I get headaches more often and sometimes painful sex. Will prp for fertility be a good treatment for me? Is there a way to know if I am in premenopause or am I in menapause? Can I be in post menapause at 44 years old? I haven’t had a menstrual cycle in two years. Is it to late for me?

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